sigma_aldrich

Sigma-Aldrich

We enable researchers to improve the quality of life. Add us on Snapchat (sigmaaldrich) for even more science fun. See today's molecule: bit.ly/Genistin

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Uracil is the pyrimidine base that "replaces" thymine in RNA. Uracil pairs with adenine in RNA like thymine does in DNA. Click on the link in the bio for more information. #adenine #iskindof #twotiming #them #goodthing #theydont #havefeelings#sigmaaldrich #chemistry #chemicals #moleculeoftheday #science #laboratory #sial #phr1581

Genistin is an inactive analog of genistein. This characterisitc makes it useful as a negative control for genistein and other tyrosine kinase inhibitors. Click on the link in the bio for more information. #inactive #butstill #useful #sigmaaldrich #chemistry #chemicals #moleculeoftheday #science #laboratory #sigma #g0897

Genistein is isoflavonoid derived from soy products.Geinstein inhibits tyrosine protein kinase and DNA topoisomerase-II. It is used to treat some cancers. Check out the link in the bio for more information. #fromsoy #to #treatingcancer #mylil #babymolecule #isall #grownup #sigmaaldrich #chemistry #chemicals #moleculeoftheday #science #laboratory #sigma #g6649

Irinotecan is the prodrug of 7-ethyl-10-hydroxycamptothecin (SN-38), which is a potent inhibitor of DNA topoisomerase I. Irinotecan is converted from produg to active drug by carboxylesterase in the tissue. Check out the link in the bio for more information. #sometimes #carboxylesterase #makesall #thedifference #sigmaaldrich #chemistry #chemicals #moleculeoftheday #science #laboratory #sigma #i1406

Vindoline is a monoterpenoid indole alkaloid produced by the Madagascar periwinkle plant. Vindoline is used in the synthesis of some anti-tumor drugs. Click on the link in the bio for more information. #periwinkleplant #whatcolor #doyouthink #itis #sigmaaldrich #chemistry #chemicals #moleculeoftheday #science #laboratory #sigma #03179

Mannose is an epimer of glucose (C2). Mannose can be converted into glucose or derived from glucose, depending on the metabolic needs of the cell. More specifically, mannose is used in the formation of glycan, which has structural and modulatory roles. Thank you @savita_es for the recommendation! Click on the link in the bio for more information. #thissugar #willbe #whatever #youwantit #tobe #versatilelittlemolecule #sigmaaldrich #chemistry #chemicals #moleculeoftheday #science #laboratory #usp #1375182

DL-3-Aminoisobutyric acid is the product of the final step of pyrimidine degradation. This compound is a β-amino acid (i.e., amino group on the β-carbon, not the α-carbon as in the 20 proteinogenic amino acids). Thank you @rchackowsky for the suggestion! Click on the link in the bio for more information. #aminoacids #pyrimidine #nottobeconfusedwithpyramids #sigmaaldrich #chemistry #chemicals #moleculeoftheday #science #laboratory #aldrich #217794

Isopropyl β-D-1-thiogalactopyranoside (IPTG, for short) is a galactose analog that cannot be metabolized and is used in cloning procedures that require induction of β-galactosidase activity. Thank you @youinthelab for your recommendation! Check out the link in the bio for more information. #amiseeingdouble #doubletrouble #cloning #sigmaaldrich #chemistry #chemicals #moleculeoftheday #science #laboratory #sial #i6758

3-Ethoxy-5,6-dibromosalicylaldehyde is a non-competitive inhibitor of inositol-requiring enzyme (IRE1). IRE1 has endonuclease activity and senses unfolded proteins in the lumen of the endoplasmic reticulum Click on the link in the bio for more information. #doesnt #liketo #compete #butstill #inhibits #sigmaaldrich #chemistry #chemicals #moleculeoftheday #science #laboratory #sml0149 #sigma

Butylboronic acid N,N,N′,N′-tetramethyl-L-tartaric acid diamide ester (yes, you read that right) is used in the preparation of biologically and pharmacologically active molecules. In general, boronic esters can be used in Suzuki–Miyaura coupling reactions. These reactions link organic boron compounds and organic halides. Click on the link in the bio for more information. #tonguetwister #prepping #those #activemolicules #sigmaaldrich #chemistry #chemicals #moleculeoftheday #science #laboratory #aldrich #518379

2-Mercaptoethanol, or β-mercaptoethanol, is used to reduce disulfide bonds in proteins prior to polyacrylamide gel electrophoresis. Breaking these bonds allows the different protein subunits to move through the gel independently. Check out the link in the bio for more information. #breakthosebonds #ifyoure #tryingto #movethrough #somegel #sigmaaldrich #chemistry #chemicals #moleculeoftheday #science #laboratory #aldrich #m6250

2,3,5-Triphenyltetrazolium chloride is used to determine whether redox reaction have occurred. It is used to indicate cellular respiration, identify myocardial infarctions in autopsies, and to test whether seeds can germinate. Click on the link in the bio for more information. #areyou #gonnagerm #ornot #thismolecule #willtell #sigmaaldrich #chemistry #chemicals #moleculeoftheday #science #laboratory #sigma #t8877

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