weillcornellResearchers at Weill Cornell Medicine have been awarded a Sohn Conference Foundation grant to develop a simple blood test that will determine how cancer spreads in children. The Foundation will fund three years of research isolating and characterizing tumor cell-derived “packages” called exosomes.
These packages, shed by pediatric cancer tumors, carry proteins and nucleic acids such as RNA or DNA, and circulate through the body to distant tissues. Dr. David Lyden, pictured, hopes that by characterizing the exosomes, his team can determine which cancers will metastasize — and where — in these cancer patients. The team’s investigation could also lead to the establishment of new biomarkers and targeted therapies for pediatric cancer patients, plus an improved understanding of metastasis in all cancers. “It will also help us identify novel biological macromolecules including proteins, lipids and genes as therapeutic targets,” Dr. Lyden said. “If we learn something in the pediatric cancer setting, it could help us learn more about other cancers.” The Sohn Conference Foundation funds pediatric cancer research, technology and programs to target cures and improve patient care.
#cancer #medicine #research #science #CareDiscoverTeach #WeillCornellMedicine
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